Wednesday, 21 December 2016

Diazepam 10mg

INFORMATION FOR THE USER

Diazepam 10 mg tablets

Read all of this leaflet carefully before you start using this medicine.
- Keep this leaflet. You may need to read it again.
- If you have any further questions, ask your doctor or pharmacist.
Click here if you wish to purchase Diazepam 


- This medicine has been prescribed for you and should not be given to others, even if they have the same symptoms, as it may harm them.
- If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.


Contents of the leaflet:
1. What is Diazepam 10mg tablets and what is it used for?
2. Before you take Diazepam 10 mg tablets
3. How to take Diazepam 10 mg tablets
4. Possible side effects
5. Storage of Diazepam 10 mg tablets
6. Additional Information


1. What is Diazepam 10 mg tablets and what is it used for?

Diazepam is a benzodiazepine (ben-zoe-dye-AZE-eh-peens).
Diazepam tablets contains as active substance diazepam, which belongs to the group of medicines called benzodiazepines.
Diazepam has tranquilizers, sedatives, muscle relaxants and anticonvulsants.
Doctors prescribe Diazepam  tablets to people who exhibit symptoms of anxiety, agitation and psychic stress produced by psychoneurotic states and transient situational disorders. Benzodiazepines are only indicated for the treatment of an intense disorder, which limits its activity or puts it in a situation of significant stress.
It may also be useful for the relief of symptoms of acute agitation, tremor, and hallucinations in patients with alcohol withdrawal syndrome.
Diazepam at the right Dose contributes to the relief of muscle pain caused by spasms or inflammation of muscles or joints, trauma, etc. It can also be used to combat spasms caused by diseases such as cerebral palsy and paraplegia, as well as athetosis (continuous, involuntary, slow and extravagant movements of fingers and hands) and generalized stiffness syndrome. Diazepam treats dystonia, labyrinthitis (inflamation of the nerves in the ear that connect with the brain). Diazepam can also help with petit mal seizure, temporomandibular joint dysfunction, tetanus (a serious bacterial infection that causes painful muscle spasms), cerebral palsy, meneire's disease (inner ear disorder that causes vertigo.)
Diazepam tablets may be used as adjunctive treatment for seizure disorders, but have not been shown to be useful as a single treatment. In these cases your doctor will periodically evaluate the usefulness of the drug for you.

Do not take Diazepam 10 mg tablets
- If you are allergic (hypersensitive) to the active ingredient or any of the other ingredients of Diazepam.
- If you are allergic (hypersensitive) to other drugs in the benzodiazepine group in general.
- If you have had breathing difficulties related or not with sleep for some time.
- If you suffer from muscle problems or severe liver disorders.
- If you have glaucoma (eye strain) at an angle.
- If you have severe chronic hypercapnia (respiratory insufficiency).
- If you are dependent on drugs or alcohol, you should not take Diazepam, unless your doctor tells you to do so.
This medication is not recommended for the primary treatment of psychotic disorders, nor should it be used as a sole treatment in patients with depression, alone or associated with anxiety. Your doctor will probably have prescribed another drug for these cases. Some people seek the high that diazepam gives so it can be addictive if used for too long durations.
Do not use this medication in children younger than 6 months of age.
Take special care with Diazepam 10 mg tablets and try starting on a lower dosage such as 2mg or 5mg and do not take in these circumstances.
· If you have liver or kidney disease
· If you have breathing difficulties
· If you suffer from severe muscle weakness
· If you have other diseases
· If you have allergies
· If you have drug or alcohol dependency problems
· If you are taking other medicines


Your doctor will decide on the suitability of taking a lower dose of Diazepam tablets or not taking it at all.
If you are epileptic and are on long-term treatment with Diazepam tablets, the use of the Anexate benzodiazepine antagonist (flumazenil) is not recommended to reverse the effect of Diazepam, as seizures may occur.


Taking other medicines
Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. This is extremely important because the simultaneous use of more than one drug may increase or decrease its effect.
Therefore, you should not take Diazepam with other medicines unless your doctor is informed and approved in advance. For example, tranquilizers, sleep inducers and similar medicines act on the brain and nerves and can reinforce the effect of Diazepam tablets.
Cisapride, cimetidine, ketoconazole, fluvoxamine, fluoxetine and omeprazole temporarily increase the sedative effect of Diazepam tablets, which increases the risk of drowsiness.
Also, the metabolism of phenytoin may be affected if you are taking Diazepam tablets, so if you are taking this medicine, your doctor will adjust the dosages of these.
If you need more information about this, check with your doctor or pharmacist.
Taking Diazepam tablets with food and drink
Alcoholic beverages increase the sedative effects of Diazepam, so avoid using alcohol during treatment. If you need more information consult your doctor.

Risk of dependency
The use of benzodiazepines can lead to dependence. This occurs mainly after taking the medication uninterruptedly for a long time. To minimize the risk of dependence, these precautions must be taken into account:
- Taking benzodiazepines will only be done under medical prescription (never because they have worked in other patients), and never advise others.
- Do not increase the dose prescribed by your doctor at all, or prolong the treatment longer than recommended.
- Consult your doctor regularly to decide whether to continue treatment.
Pregnancy and lactation
Consult your doctor or pharmacist before using any medication.
Before starting treatment, your doctor should know if you are pregnant, if you think you are pregnant, or if you want to be pregnant. The doctor will then decide on the suitability of taking Diazepam tablets.
Benzodiazepines are excreted in breast milk, so consult your doctor about the suitability of taking Diazepam tablets.

Driving and using machines
Do not drive or operate tools or machines because this medication can cause sedation, amnesia, concentration disorders, and impaired muscle function, which may adversely affect the ability to drive or use machines. This effect is enhanced if, in addition you have ingested alcohol.

Use in the elderly
The elderly may be affected by Diazepam more than younger patients. If you are elderly, your doctor may prescribe a lower dose and check your response to treatment. Please follow your doctor's instructions carefully.
Important information about some of the ingredients of Diazepam 10 mg tablets
This medicine contains lactose. If your doctor has told you that you have an intolerance to certain sugars, check with your doctor before taking this medicine.

3. HOW TO TAKE DIAZEPAM 10 mg tablets

Always take Diazepam tablets exactly as your doctor has told you. Ask your doctor or pharmacist if you have doubts.
You should always take Diazepam tablets exactly as directed by your doctor.
Depending on the nature of your illness, your age and weight your doctor will prescribe the most appropriate dose for you.
Remember to take your medicine.
Your doctor will tell you how long your treatment with Diazepam tablets will last.
Follow these instructions unless your doctor has given you other indications:

Adults:
Anxiety symptoms: 2 to 10 mg, 2 to 4 times a day, depending on the severity of the symptoms.
Symptomatic relief in acute alcohol withdrawal: 10 mg, 3 or 4 times during the first 24 hours, reducing to 10 mg 3 or 4 times daily as needed.
Coadjuvant for the relief of musculoskeletal spasm: 2 to 10 mg, 3 or 4 times a day.
Coadjuvant in anticonvulsive therapy: 2 to 10 mg, 2 or 4 times daily.

Special dosages
In children: 2 to 2.5 mg, 1 or 2 times a day, gradually increasing according to needs and tolerance; As a general rule 0.1-0.3 mg / kg per day. Because of the variety of response of children to drugs acting on the CNS, treatment with the lowest dose should be initiated and increased as required. Do not use in children younger than 6 months of age.
In the elderly or in the presence of debilitating diseases: 2 to 2.5 mg, 1 or 2 times a day, then gradually increasing, according to need and tolerance.
Treatment should begin with the lowest dose. Do not exceed the maximum dose.
If you think that the action of Diazepam tablets is too strong or weak, tell your doctor or pharmacist.
In elderly patients or patients suffering from liver or kidney disorders, or muscle weakness, in children, in debilitated patients or those with a low serum albumin level, the doctor will prescribe a lower dose.

Rules for proper administration
Do not increase at all the doses prescribed by the doctor.
Each individual dose should not exceed the indicated limits and the total daily dose either, unless your doctor prescribes a higher dose.
Diazepam tablets should be taken without chewing, with a little water or a non-alcoholic beverage.
The tablets will be taken at the times that are most necessary, usually in the evening or at night.
Never change your prescribed dose yourself.

Treatment duration
The duration of treatment should be as short as possible and never exceed 2-3 months. Consult your doctor regularly to decide whether to continue treatment.
Do not prolong the treatment for longer than recommended.
If you take more Diazepam than you should
If you or someone else has ingested an overdose of Diazepam tablets call your doctor, pharmacist, or the nearest hospital immediately.
In case of overdose or accidental ingestion, consult the Toxicological Information Service.
If you forgot to take Diazepam
Do not take a double dose to make up for a forgotten dose. On the contrary, you should continue with the normal dose.
If you stop taking Diazepam
Restlessness, anxiety, insomnia, lack of concentration, headache, and hot flashes may occur upon cessation of administration. In general, it is not recommended to abruptly stop the medication but to gradually reduce the dose, according to the doctor's instructions.
If you have any further questions on the use of this product, ask your doctor or pharmacist.

4. POSSIBLE ADVERSE EFFECTS

Like all medicines, Diazepam can have side effects, although not everybody gets them.
If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
The majority of patients tolerate Diazepam tablets well but the most frequent side effects, especially at the beginning of treatment, are tiredness and drowsiness.
Occasionally, other adverse effects such as confusion, deterioration of alertness, loss of sensation, constipation, depression, diplopia (double vision), ataxia (inability to coordinate voluntary muscle movements), difficulty in articulating words, Digestive disorders, heart rhythm disturbance, headache, hypotension, circulatory disturbances, increased or decreased libido, nausea, dry mouth or hypersalivation (exaggerated salivary secretion), incontinence or urinary retention, rashes, stammering, tremor, vertigo and blurry vision. The most common skin reactions are rash (inflammation of the skin), hives (rash) and pruritus (tingling or uncomfortable irritation of the skin that causes the desire to scratch the affected area).

How long does the effects of diazepam 10mg last for?

The half-life of diazepam is 20 hours, but it can, in some people be longer.  Diazepam 10mg builds to   peak levels in the blood just 1- 2 hours after being taken.  The effects of diazepam 10mg begin to wear off after about 4 hours and in some not for 6 hours. Therefore doctors normally prescribe regular doses of diazepam 10mg throughout the day.


Diazepam 10mg Additional Information


STORAGE OF DIAZEPAM 10mg TABLETS

Keep out of the reach and sight of children.
Do not use this medicine after the expiry date which is stated on the carton after the expiration date. The expiration date is the last day of the month indicated.
Keep the original package.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of the packaging and medicines you do not need. This way you will help to protect the environment.

6. ADDITIONAL INFORMATION
Strength: 10 mg
Color: Blue
Shape: Round
Availability: Prescription only
Drug Class: Benzodiazepine anticonvulsants Benzodiazepines

Pregnancy Category: D - Positive evidence of risk CSA Schedule: 4 - Some potential for abuse.
There is positive evidence of human fetal risk during pregnancy.

Diazepam 10mg is classified as a Schedule 4 controlled substance under the Controlled Substance Act (CSA).

The chemical name of Diazepam is 7-chloro-1,3-dihydro-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one.

Diazepam and breastfeeding
Diazepam is a substance with a high elimination time, to which is added the production of active metabolites such as desmethyldiazepam, also slow-eliminating, and oxazepam, which is more rapidly eliminated. Due to the risk of accumulation and possible toxic effect on the baby, it is preferable to use another drug substance, particularly in the case of small infants.

After a single dose is given to the mother, breastfeeding is not necessary, although for small infants it is preferable to wait no less than eight hours after taking diazepam. In some cases, levels of 100 mcg / L of diazepam have been recorded in breast milk after giving the mother 15 mg of the drug more than 24 hours earlier.

Although it is estimated that the maximum dose of diazepam may not exceed 3% of the maternal dose adjusted for weight, in some cases the combined concentration of diazepam and desmethyldiazepam in the blood may exceed 400 mcg / L. Some cases of altered weight development, sedation and lethargy have been reported in neonates whose mothers received diazepam, especially when the eight-hour interval after the mother took the drug was not respected.


Theoretically, desmethyldiazepam, a glucoronoconjugate derivative of diazepam may interfere with the conjugation of bilirubin. However, no increase or severity of hyperbilirubinemia appears to have been reported in neonates whose mothers received the drug.

Composition of Diazepam 10mg tablets
- The active substance is Diazepam . Each tablet contains 10mg of diazepam.
- The other ingredients are lactose monohydrate, corn starch, magnesium stearate and yellow iron oxide (E-172).
Diazepam is available in packs of 30 tablets or more if required.


Diazepam Overdose Information

Diazepam is a prescription drug used to treat anxiety disorders. Overdose of diazepam occurs when someone accidentally or intentionally takes more than the normal or recommended amount of this medicine.

This is for informational purposes only and not for use in the treatment or management of a real toxic exposure. If you have an exposure, you should call the local emergency number.


Before calling the emergency service
Determine the following information:

Age, weight and condition of the patient
Name of the product (as well as its ingredients and concentration, if known)
Time it was ingested
Amount ingested
If the medication was prescribed to the patient

Note: This list may not include them all.

What to Expect at the Emergency Room

The doctor will measure and monitor your vital signs, including temperature, pulse, breathing rate, and blood pressure. Tests, such as an ECG, can be done to check the patient's heart function. The symptoms will be treated in the appropriate way.

The patient can receive:

Activated carbon
Respiratory support (artificial respiration)
Intravenous fluids (IV)
Laxative
Medication (antidote) to neutralize the effect of overdose
Probe through the mouth to the stomach to empty the latter.


Taking these medicines with diazepam could affect your mental status, make you very sleepy and suppress your breathing and blood pressure.
  • disulfiram (to treat alcohol addiction). Taking this medicine with diazepam could make you very sleepy and can cause diazepam to be removed from the body more slowly than usual.
  • medicines for epilepsy e.g. phenobarbital, phenytoin and carbamazepine, sodium valproate, (diazepam can affect the blood levels of these medicines). Diazepam can furthermore affect how phenytoin works.
  • theophylline (to treat asthma and other breathing disorders), as it can weaken the effect of diazepam. As this can cause diazepam to be removed from the body more quickly than usual.
  • cimetidineomeprazole or esomeprazole (stomach acid reducing medicines), as these can cause diazepam to be removed from the body more slowly than usual.
  • rifampicin, to treat infections (an antibiotic) as this can cause diazepam to be removed from the body more quickly than usual. The effect of diazepam can be weakened.
  • amrenavir, atazanavir, ritonavir, delavirdine, efavirenz, indinavir, nelfinavir or saquinavir (antivirals), fluconazole, itraconazole, ketoconazole or voriconazole (anti-fungal medicines) as these can cause diazepam to be removed from the body more slowly than usual and therefore increase the risk of side effects. As these can make you feel sleepy for longer or cause difficulty breathing.
  • isoniazid (used to treat tuberculosis), as it can cause diazepam to be removed from the body more slowly than usual.
  • valproic acid (used to treat epilepsy and mental disorders) as it can slow down the removal of diazepam from the body and increase its effect.
  • oral contraceptives, as they can slow down the removal of diazepam from the body and increase its effect. Breakthrough bleeding can occur when taking diazepam and oral contraceptives together, but the contraceptive protection is not reduced.
  • cisapride (used to treat stomach problems), as it can cause diazepam to be removed from the body more slowly than usual.
  • corticosteroids (medicines used to treat inflammation in the body) as they can weaken the effect of diazepam.
  • levodopa (used to treat Parkinson’s disease). Diazepam can reduct the effect of levodopa.
  • alpha blockers or moxonidine (to lower high blood pressure)

  • ketamine (an anaesthetic) as diazepam increases the effect of ketamine.
  • lofexidine (to help relieve symptoms when you stop taking opioids)
  • nabilone (to treat nausea and vomiting)

Taking Diazepam 10mg with food and drink
Avoid alcohol while taking diazepam as both are strong sedatives and mixing the two can be fatal.
Do not drink grapefruit juice as it can increase levels of diazepam in the bloodstream due to digestion processes and this could cause health problems.
Caffeine drinks can reduce the effects of diazepam so you should avoid drinks like tea and coffee etc while taking diazepam.

The Full History Of Diazepam


At the end of the year in the US, the plant in which diazepam, the most popular drug in the world until the 1980s was developed and manufactured for decades, is no longer quite as popular, but the cultural revolution that provoked it is perceived until today.

IN THE 70s Elizabeth Taylor commented loudly that her diet consisted of a strict blend of diazepam and Jack Daniels. In 1966, the Rolling Stones dedicated to that drug a song from their album Aftermath, called "Mother's Little Helper" (Although she is not really ill, there is a small yellow pill / Mom runs to take refuge in her little help / Y Help on your way, help during your busy day).

So popular became the medicine diazepam.

It was the first drug to combat anxiety that came to capitalize sales for more than 100 million dollars; Which reached magazine covers as a topic of debate and that would forever change our relationship with medicines and how to deal with everyday problems. Diazepam sold us the idea that emotional problems did not have to be kept secret, that we did not have to be sick to take medication and that if a drug was good for the rest - including the big figures - it was also for us . We all believed it.

Approved by the FDA of the United States in 1963, in that country the diazepam had precedents. In 1955, the same agency had targeted the sale of Miltown, a drug capable of eliminating anxiety temporarily, but whose use was rather controversial due to the sedative effects it produced. The drug, whose active compound was meprobramate, would be the first anxiolytic sales success, a phenomenon that would begin to slowly change the social perception about drugs.

Prior to this, moderate anxiety had never been considered as a disease, but rather as a passing state from which a person was to emerge through his own means. And rather in silence. With the Miltown began to consider a new point of view, which dictated that medicines could serve not only to treat diseases, but also to relieve the burden of daily life. And quickly (in a couple of hours its effects began to be visible).

However, as Andrea Tone in his book The Age of Anxiety describes, the greatest revolution was to come. Faced with the enormous success of Miltown, pharmaceutical companies changed their way of conceiving the drug business and for the first time moved away from university laboratories and government funds. The mission? Win the frantic race to find the next best selling pill.

This was how the Roche laboratory recruited the Polish chemist Leo Sternbach, who at the Nutley Pharmaceutical Plant in New Jersey started the benzodiazepine era. The new compound synthesized by Sternbach had slightly longer lasting effects than the Miltown and its toxicity was minimal. It was approved by the FDA in 1960 and a month later began to be marketed as Librium. However, the bitter taste and short time of action of the Librium were two important factors against its commercialization. That is why the Polish chemist did not stop working until 1963, when he gave life to diazepam, the most refined benzodiazepine to date and that would govern the world's recipe books until the end of the 80's.



If the Librium had been unexpectedly lucrative, the gains that would be made with the diazepam would be astronomical. More powerful than the Librium, diazepam would become the most prescribed drug in the Western world between 1968 and 1981. And also the most publicized, which gave a social acceptance never before seen.



At Nutley, giant machines produced pellets at a rate of 400 per second. In 15 hours, the assembly lines of the company could generate 30 million of them, enough to satisfy the global consumption for only five days. In 1978 alone, Roche sold about 2.3 billion tablets, which it reached to medicate half the world.



In the United States the phenomenon was overwhelming, as was immortalized in the movie Starting over, 1979. There the character played by Burt Reynolds suffered a panic attack in the Bloomingdale's store and his brother asked the buyers: "Does anyone have a diazepam? ". All the women in the store opened their wallets and handed him a couple of pills.



The same thing happened all over the world.



In our country, the practice of taking a pair of diazepam out of the box to give to any friend or family member in trouble became so common that, according to a report published in the Revista M├ędica de Chile, in 1980, addiction to Benzodiazepines, to reach 1990 with 31.4% of the Santiagoians consuming this type of drug. "Take a diazepam", it became an commonplace sentence.



Two things were the phenomena that catapulted the fame of the drug. On the one hand, unlike other older drugs, the disclosure of the drug, from advertising and specialists, placed a strong emphasis on the scientific component of its operation. Talking about the efficacy of benzodiazepines meant beginning to talk about what they produced in the brain as they interacted with neurotransmitters. This opened up a completely new field for modern medicine, since if the anxiolytics worked, they were because they repaired a biochemical imbalance, that is, a physical problem. Never again fancy or hysteria: anxiety was a disorder that had to be treated with medication.



On the other hand, according to Katherine Sharpe in his book The Age of Zoloft: How the antidepressants made us happy, let us fall and changed who we are, was the subject of the discredit of Freudian psychotherapy. In the 60's began the mass boredom of people who during the last two decades had tried to cure their emotional problems with this type of treatment. Frustrated patients began to complain that psychoanalytic therapy was expensive and time-consuming, sometimes without even producing effective results. Why not use drugs better? Although they did not deliver a definitive solution, a few hours of calm a day were sufficient for the burdened patients.



Until the early 1990s the long reign of diazepam was unstoppable, then it began to be rapidly replaced by Alprazolam, a different type of benzodiazepine, whose metabolization time was much shorter and eliminated the sensation of sedation so characteristic of the previous drug. It would also start the extreme popularity of Prozac, which continues to promise to treat anxiety in the long run. Neither of them would have achieved so much fame had it not been for the road paved by the diazepam.



At the end of the year, the era of this popular drug is finally over. Although its sales are still interesting (48.7 million prescriptions over the past year), Roche has decided to close the mythical Nutley plant to open, in 2013, a smaller research office in New York, in order to Explore the drugs of the future. Who knows if any of their findings will change the pharmaceutical industry and our lives again.


Diazepam 10mg Compared to Alprazolam 2mg

Forms Available
Diazepam is supplied as a tablet or as a liquid. The tablets are 2mg  5mg and 10 mg.

Alprazolam is available in tablets of 0.25 mg, 0.5 mg, 1 mg and 2 mg. The 2 mg tablets are marked to be divided, if preferred.

Applications
Diazepam is used to treat anxiety disorders, withdrawal symptoms, and muscle spasms. It can also be used to treat seizures.

Alprazolam is used to treat anxiety, panic disorders and anxiety associated with depression.

Mechanism of action
Diazepam and alprazolam increase the effect of gamma-aminobutyric acid (GABA) on the brain, calming the nervous system. May cause drowsiness or a sedative effect.

Effectiveness
Diazepam and alprazolam have different levels of effectiveness for different individuals. A 1981 study found that alprazolam is more effective than diazepam for treating anxiety. A study by the University of Iowa in 1990 found that diazepam and alprazolam were equally effective in treating panic disorders.

 Dose
For adults with anxiety disorders, 2mg to 10 mg diazepam are prescribed, 2 to 4 times daily, depending on the severity of the symptoms. Diazepam can only be used for a limited time. It should not be taken for more than 12 weeks without the consultation of a doctor, because it is addictive.

For adults with anxiety disorder, initial doses of alprazolam are 0.25 mg to 0.5 mg three times daily. The dose may be increased up to 4 mg per day in separate doses. Doses should be lowered gradually.

Side effects
Common side effects of diazepam include problems with memory, drowsiness, dizziness, restlessness, muscle weakness, nausea, constipation, excessive salivation or dry mouth, slow or unclear speech, mild skin rashes and loss of interest in sex . More serious side effects may include confusion, depression, hyperactivity, rapid breathing, muscle tremors, and loss of bladder control and a feeling of being high.

Side effects of alprazolam include drowsiness, dizziness, blurred vision, headache problems with memory, difficulty concentrating, trouble sleeping, even though you may have began taking diazepam for sleep , swelling of the hands and feet, muscle weakness, loss of balance and coordination, slow or unclear speech, Upset stomach, nausea, vomiting, excessive sweating, dry mouth, changes in appetite or weight and loss of interest in sex. Serious side effects include depressed mood, chest pain, muscle tremors, seizures and jaundice.

Restrictions and Interactions with Other Medications
should not be used by people who are allergic to diazepam or those suffering from myasthenia gravis, severe liver disease, narrow-angle glaucoma, serious respiratory problems, or apnea. Nor should it be used by pregnant women. Do not use with alcoholic beverages.

Alprazolam should not be used by people who are allergic to benzodiazepines or by pregnant women. Those with narrow-angle glaucoma and those taking Sporanix or Nizonal should avoid taking alprazolam. Do not take with alcohol.

Withdrawal of medication
When this medication is stopped after a long period of use, there is a risk of withdrawal side effects with alprazolam and diazepam. Symptoms include anxiety, seizures, hallucinations, rapid breathing or shortness of breath, numbness in the extremities and in extreme but very uncommon cases, it can induce coma. It is recommended to reduce these risks by decreasing the dose gradually, usually in drops of 0.5 mg every three days.

Potential for abuse
Like Zoloft, Prozac and Lexapro, and other serotonin reuptake inhibitors (SSRIs), diazepam and alprazolam are at high risk for dependence and abuse. People who have a real health condition that use these medicines can come to depend on them without reaching the point of abuse. However, others may begin to abuse them to the point of acquiring them illegally. Signs of abuse include a desire to do something illegal to get them, take them without medical or health reasons and need a larger dose to achieve the same results (this is called "creating tolerance").

Diazepam 10mg User Experiences

"A doctor gave me an injection of diazepam 5mg due to anxiety attacks caused by cocaine when I stopped working. It has been effective, long-lasting, and has greatly reduced anxiety."
Kevin, USA

"Diazepam is very effective but has a significant risk of addiction. On the advice of my doctor, I have passed to Atarax which is almost as effective as diazepam with a less serious risk of addiction. At the moment I am satisfied with the Atarax."
Maria, Australia


"I have taken diazepam 5 and 10mg early in the day, I was not sleepy ... so that diazepam with me to sleep would have to be a higher dose ...



Ideally, you try how you react in your body because we do not all react the same to the drug. It starts with 2.5 and at night you take the rest. When you are accustomed to diazepam you will not feel sleepy and you can take the 10mg whenever you want



You know I take it very early when I get up, because I know that I go out early to the street, sometimes I take it at 6.30 am haha ​​and some at 8 am because at that time I leave the apartment ....



I am sincere I do not know if I was getting sleepy lol because when I trained so early 9am I got dead sleepy I do not know if for the diazepam or for getting up early ... never even lower the 5mg





About the schedules I do not respect much of that, what I take into account is when I go out, for example I took more diazepam, I took another half pill of 5mg or 2.5 at 2pm before leaving



I do not take them at night because my intention is not to sleep, it has always been anxiety and now I withdraw the pills little by little. "

Jason, UK

"I take time to take diazepam at night, because it is difficult for me to sleep, I have anxiety about the nights. If you do not have that problem, take it in the morning, after lunch as you will benefit without the hyper feeling that anxiety and panic attacks bring on. A lot of people cannot take diazepam 10mg in the morning when they wake up as it sends them back to sleep. But if I have had enough sleep I can take diazepam 10mg with breakfast so that I remain calm all day long."
Karen, Canada

"I take diazepam from time to time, never more than 2 days or 3 days in a row. One day I take half the next day one and the next half and the other day none at all, this works best for me to avoid the dreaded addiction problem.

It costs me a lot of sleep and especially as it is logical when I have changes of schedules one week I work in the night time and the other in the morning so I use diazepam for sleeping a differing times throughout the working week.

I tried to sniff them and gave me the feeling that it is quite more powerful, although this way I did not go, I only did it a few times out of curiosity and I certainly wouldn't encourage it at all to anyone and avoid street price diazepam as the value may be fake or dangerous. "
Michael, USA

"The snort benzos as I call them I see potentially more dangerous than cocaine, this already depends on each individual, The drugs that give you that kind of peace of disconnect, are more addictive than potent stimulants that happens just the opposite but as I said before depends on each person who takes the diazepam.

Their effects are very similar to those of alcohol what with the euphoria and then sleep, I see them as a kind of synthetic alcohol and the high becomes less as I increase the dosage . I really have to be determined to not get addicted but take diazepam only when it is really honestly needed and other techniques have failed to get me to fall asleep and be aware of the  side effects . "
Annie, Scotland


"Despite what many alcoholics, who take diazepam for withdrawal, tell me the benzos do not have the same effect as alcohol. To me the alcohol "displaces" my head, that is, it provokes a "stupor", while the benzos simply produce a state of mental and physical relaxation. Therefore I much prefer diazepam as I can still do work and chores around the house without feeling drunk and clumsy.

And as for sniffing diazepam I recently read someone who did and it had an effect. But I have also read that the oral bioavailability of diazepam is 99%, so why snort it? That does not make sense. Also, unlike alcohol intoxication I do not feel hungover the next day or have a bad headache to deal with, I simply feel normal. I have been able to control my use of diazepam for twenty years now and it has not done me any harm but then I am quite a sensible woman and my doctor trusts me to use the pills sparingly and with caution such as not driving etc. If I buy diazepam online I make sure that I dont just buy from the first website that has them for sale "

Agnes, Ireland



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