Friday, 3 March 2017

Diazepam Compared With Xanax

Forms Available
Diazepam is supplied as a tablet or as a liquid. The tablets are 2mg  5mg and 10 mg.

Alprazolam is available in tablets of 0.25 mg, 0.5 mg, 1 mg and 2 mg. The 2 mg tablets are marked to be divided, if preferred.

Applications
Diazepam is used to treat anxiety disorders, withdrawal symptoms, and muscle spasms. It can also be used to treat seizures.

Alprazolam is used to treat anxiety, panic disorders and anxiety associated with depression.

Mechanism of action
Diazepam and alprazolam increase the effect of gamma-aminobutyric acid (GABA) on the brain, calming the nervous system. May cause drowsiness or a sedative effect.

Effectiveness
Diazepam and alprazolam have different levels of effectiveness for different individuals. A 1981 study found that alprazolam is more effective than diazepam for treating anxiety. A study by the University of Iowa in 1990 found that diazepam and alprazolam were equally effective in treating panic disorders.

 Dose
For adults with anxiety disorders, 2mg to 10 mg diazepam are prescribed, 2 to 4 times daily, depending on the severity of the symptoms. Diazepam can only be used for a limited time. It should not be taken for more than 12 weeks without the consultation of a doctor, because it is addictive.

For adults with anxiety disorder, initial doses of alprazolam are 0.25 mg to 0.5 mg three times daily. The dose may be increased up to 4 mg per day in separate doses. Doses should be lowered gradually.

Side effects
Common side effects of diazepam include problems with memory, drowsiness, dizziness, restlessness, muscle weakness, nausea, constipation, excessive salivation or dry mouth, slow or unclear speech, mild skin rashes and loss of interest in sex . More serious side effects may include confusion, depression, hyperactivity, rapid breathing, muscle tremors, and loss of bladder control and a feeling of being high.

Side effects of alprazolam include drowsiness, dizziness, blurred vision, headache problems with memory, difficulty concentrating, trouble sleeping, even though you may have began taking diazepam for sleep , swelling of the hands and feet, muscle weakness, loss of balance and coordination, slow or unclear speech, Upset stomach, nausea, vomiting, excessive sweating, dry mouth, changes in appetite or weight and loss of interest in sex. Serious side effects include depressed mood, chest pain, muscle tremors, seizures and jaundice.

Restrictions and Interactions with Other Medications
should not be used by people who are allergic to diazepam or those suffering from myasthenia gravis, severe liver disease, narrow-angle glaucoma, serious respiratory problems, or apnea. Nor should it be used by pregnant women. Do not use with alcoholic beverages.

Alprazolam should not be used by people who are allergic to benzodiazepines or by pregnant women. Those with narrow-angle glaucoma and those taking Sporanix or Nizonal should avoid taking alprazolam. Do not take with alcohol.

Withdrawal of medication
When this medication is stopped after a long period of use, there is a risk of withdrawal side effects with alprazolam and diazepam. Symptoms include anxiety, seizures, hallucinations, rapid breathing or shortness of breath, numbness in the extremities and in extreme but very uncommon cases, it can induce coma. It is recommended to reduce these risks by decreasing the dose gradually, usually in drops of 0.5 mg every three days.

Potential for abuse
Like Zoloft, Prozac and Lexapro, and other serotonin reuptake inhibitors (SSRIs), diazepam and alprazolam are at high risk for dependence and abuse. People who have a real health condition that use these medicines can come to depend on them without reaching the point of abuse. However, others may begin to abuse them to the point of acquiring them illegally. Signs of abuse include a desire to do something illegal to get them, take them without medical or health reasons and need a larger dose to achieve the same results (this is called "creating tolerance").

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