Friday, 3 March 2017

Welcome to the Diazepam Information Website!

Welcome!
This website is based around the drug diazepam with pages all about it. You can read user experiences of diazepam along with dosages information guide and how to safely use the medication to combat anxiety related disorders.

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Reviews of Diazepam User Experiences and the High

Diazepam 10mg User Experiences
"A doctor gave me an injection of diazepam 5mg due to anxiety attacks caused by cocaine when I stopped working. It has been effective, long-lasting, and has greatly reduced anxiety."
Kevin, USA

"Diazepam is very effective but has a significant risk of addiction. On the advice of my doctor, I have passed to Atarax which is almost as effective as diazepam with a less serious risk of addiction. At the moment I am satisfied with the Atarax."
Maria, Australia


"I have taken diazepam 5 and 10mg early in the day, I was not sleepy ... so that diazepam with me to sleep would have to be a higher dose ...



Ideally, you try how you react in your body because we do not all react the same to the drug. It starts with 2.5 and at night you take the rest. When you are accustomed to diazepam you will not feel sleepy and you can take the 10mg whenever you want



You know I take it very early when I get up, because I know that I go out early to the street, sometimes I take it at 6.30 am haha ​​and some at 8 am because at that time I leave the apartment ....



I am sincere I do not know if I was getting sleepy lol because when I trained so early 9am I got dead sleepy I do not know if for the diazepam or for getting up early ... never even lower the 5mg





About the schedules I do not respect much of that, what I take into account is when I go out, for example I took more diazepam, I took another half pill of 5mg or 2.5 at 2pm before leaving



I do not take them at night because my intention is not to sleep, it has always been anxiety and now I withdraw the pills little by little. "

Jason, UK

"I take time to take diazepam at night, because it is difficult for me to sleep, I have anxiety about the nights. If you do not have that problem, take it in the morning, after lunch as you will benefit without the hyper feeling that anxiety and panic attacks bring on. A lot of people cannot take diazepam 10mg in the morning when they wake up as it sends them back to sleep. But if I have had enough sleep I can take diazepam 10mg with breakfast so that I remain calm all day long."
Karen, Canada

"I take diazepam from time to time, never more than 2 days or 3 days in a row. One day I take half the next day one and the next half and the other day none at all, this works best for me to avoid the dreaded addiction problem.

It costs me a lot of sleep and especially as it is logical when I have changes of schedules one week I work in the night time and the other in the morning so I use diazepam for sleeping a differing times throughout the working week.

I tried to sniff them and gave me the feeling that it is quite more powerful, although this way I did not go, I only did it a few times out of curiosity and I certainly wouldn't encourage it at all to anyone and avoid street price diazepam as the value may be fake or dangerous. "
Michael, USA

"The snort benzos as I call them I see potentially more dangerous than cocaine, this already depends on each individual, The drugs that give you that kind of peace of disconnect, are more addictive than potent stimulants that happens just the opposite but as I said before depends on each person who takes the diazepam.

Their effects are very similar to those of alcohol what with the euphoria and then sleep, I see them as a kind of synthetic alcohol and the high becomes less as I increase the dosage . I really have to be determined to not get addicted but take diazepam only when it is really honestly needed and other techniques have failed to get me to fall asleep and be aware of the  side effects . "
Annie, Scotland


"Despite what many alcoholics, who take diazepam for withdrawal, tell me the benzos do not have the same effect as alcohol. To me the alcohol "displaces" my head, that is, it provokes a "stupor", while the benzos simply produce a state of mental and physical relaxation. Therefore I much prefer diazepam as I can still do work and chores around the house without feeling drunk and clumsy.

And as for sniffing diazepam I recently read someone who did and it had an effect. But I have also read that the oral bioavailability of diazepam is 99%, so why snort it? That does not make sense. Also, unlike alcohol intoxication I do not feel hungover the next day or have a bad headache to deal with, I simply feel normal. I have been able to control my use of diazepam for twenty years now and it has not done me any harm but then I am quite a sensible woman and my doctor trusts me to use the pills sparingly and with caution such as not driving etc. If I buy diazepam online I make sure that I dont just buy from the first website that has them for sale "

Agnes, Ireland


Diazepam Compared With Xanax

Forms Available
Diazepam is supplied as a tablet or as a liquid. The tablets are 2mg  5mg and 10 mg.

Alprazolam is available in tablets of 0.25 mg, 0.5 mg, 1 mg and 2 mg. The 2 mg tablets are marked to be divided, if preferred.

Applications
Diazepam is used to treat anxiety disorders, withdrawal symptoms, and muscle spasms. It can also be used to treat seizures.

Alprazolam is used to treat anxiety, panic disorders and anxiety associated with depression.

Mechanism of action
Diazepam and alprazolam increase the effect of gamma-aminobutyric acid (GABA) on the brain, calming the nervous system. May cause drowsiness or a sedative effect.

Effectiveness
Diazepam and alprazolam have different levels of effectiveness for different individuals. A 1981 study found that alprazolam is more effective than diazepam for treating anxiety. A study by the University of Iowa in 1990 found that diazepam and alprazolam were equally effective in treating panic disorders.

 Dose
For adults with anxiety disorders, 2mg to 10 mg diazepam are prescribed, 2 to 4 times daily, depending on the severity of the symptoms. Diazepam can only be used for a limited time. It should not be taken for more than 12 weeks without the consultation of a doctor, because it is addictive.

For adults with anxiety disorder, initial doses of alprazolam are 0.25 mg to 0.5 mg three times daily. The dose may be increased up to 4 mg per day in separate doses. Doses should be lowered gradually.

Side effects
Common side effects of diazepam include problems with memory, drowsiness, dizziness, restlessness, muscle weakness, nausea, constipation, excessive salivation or dry mouth, slow or unclear speech, mild skin rashes and loss of interest in sex . More serious side effects may include confusion, depression, hyperactivity, rapid breathing, muscle tremors, and loss of bladder control and a feeling of being high.

Side effects of alprazolam include drowsiness, dizziness, blurred vision, headache problems with memory, difficulty concentrating, trouble sleeping, even though you may have began taking diazepam for sleep , swelling of the hands and feet, muscle weakness, loss of balance and coordination, slow or unclear speech, Upset stomach, nausea, vomiting, excessive sweating, dry mouth, changes in appetite or weight and loss of interest in sex. Serious side effects include depressed mood, chest pain, muscle tremors, seizures and jaundice.

Restrictions and Interactions with Other Medications
should not be used by people who are allergic to diazepam or those suffering from myasthenia gravis, severe liver disease, narrow-angle glaucoma, serious respiratory problems, or apnea. Nor should it be used by pregnant women. Do not use with alcoholic beverages.

Alprazolam should not be used by people who are allergic to benzodiazepines or by pregnant women. Those with narrow-angle glaucoma and those taking Sporanix or Nizonal should avoid taking alprazolam. Do not take with alcohol.

Withdrawal of medication
When this medication is stopped after a long period of use, there is a risk of withdrawal side effects with alprazolam and diazepam. Symptoms include anxiety, seizures, hallucinations, rapid breathing or shortness of breath, numbness in the extremities and in extreme but very uncommon cases, it can induce coma. It is recommended to reduce these risks by decreasing the dose gradually, usually in drops of 0.5 mg every three days.

Potential for abuse
Like Zoloft, Prozac and Lexapro, and other serotonin reuptake inhibitors (SSRIs), diazepam and alprazolam are at high risk for dependence and abuse. People who have a real health condition that use these medicines can come to depend on them without reaching the point of abuse. However, others may begin to abuse them to the point of acquiring them illegally. Signs of abuse include a desire to do something illegal to get them, take them without medical or health reasons and need a larger dose to achieve the same results (this is called "creating tolerance").

The Complete History of Diazepam

The Full History Of Diazepam

At the end of the year in the US, the plant in which diazepam, the most popular drug in the world until the 1980s was developed and manufactured for decades, is no longer quite as popular, but the cultural revolution that provoked it is perceived until today.

IN THE 70s Elizabeth Taylor commented loudly that her diet consisted of a strict blend of diazepam and Jack Daniels. In 1966, the Rolling Stones dedicated to that drug a song from their album Aftermath, called "Mother's Little Helper" (Although she is not really ill, there is a small yellow pill / Mom runs to take refuge in her little help / Y Help on your way, help during your busy day).

So popular became the medicine diazepam.

It was the first drug to combat anxiety that came to capitalize sales for more than 100 million dollars; Which reached magazine covers as a topic of debate and that would forever change our relationship with medicines and how to deal with everyday problems. Diazepam sold us the idea that emotional problems did not have to be kept secret, that we did not have to be sick to take medication and that if a drug was good for the rest - including the big figures - it was also for us . We all believed it.

Approved by the FDA of the United States in 1963, in that country the diazepam had precedents. In 1955, the same agency had targeted the sale of Miltown, a drug capable of eliminating anxiety temporarily, but whose use was rather controversial due to the sedative effects it produced. The drug, whose active compound was meprobramate, would be the first anxiolytic sales success, a phenomenon that would begin to slowly change the social perception about drugs.

Prior to this, moderate anxiety had never been considered as a disease, but rather as a passing state from which a person was to emerge through his own means. And rather in silence. With the Miltown began to consider a new point of view, which dictated that medicines could serve not only to treat diseases, but also to relieve the burden of daily life. And quickly (in a couple of hours its effects began to be visible).

However, as Andrea Tone in his book The Age of Anxiety describes, the greatest revolution was to come. Faced with the enormous success of Miltown, pharmaceutical companies changed their way of conceiving the drug business and for the first time moved away from university laboratories and government funds. The mission? Win the frantic race to find the next best selling pill.

This was how the Roche laboratory recruited the Polish chemist Leo Sternbach, who at the Nutley Pharmaceutical Plant in New Jersey started the benzodiazepine era. The new compound synthesized by Sternbach had slightly longer lasting effects than the Miltown and its toxicity was minimal. It was approved by the FDA in 1960 and a month later began to be marketed as Librium. However, the bitter taste and short time of action of the Librium were two important factors against its commercialization. That is why the Polish chemist did not stop working until 1963, when he gave life to diazepam, the most refined benzodiazepine to date and that would govern the world's recipe books until the end of the 80's.



If the Librium had been unexpectedly lucrative, the gains that would be made with the diazepam would be astronomical. More powerful than the Librium, diazepam would become the most prescribed drug in the Western world between 1968 and 1981. And also the most publicized, which gave a social acceptance never before seen.



At Nutley, giant machines produced pellets at a rate of 400 per second. In 15 hours, the assembly lines of the company could generate 30 million of them, enough to satisfy the global consumption for only five days. In 1978 alone, Roche sold about 2.3 billion tablets, which it reached to medicate half the world.



In the United States the phenomenon was overwhelming, as was immortalized in the movie Starting over, 1979. There the character played by Burt Reynolds suffered a panic attack in the Bloomingdale's store and his brother asked the buyers: "Does anyone have a diazepam? ". All the women in the store opened their wallets and handed him a couple of pills.



The same thing happened all over the world.



In our country, the practice of taking a pair of diazepam out of the box to give to any friend or family member in trouble became so common that, according to a report published in the Revista M├ędica de Chile, in 1980, addiction to Benzodiazepines, to reach 1990 with 31.4% of the Santiagoians consuming this type of drug. "Take a diazepam", it became an commonplace sentence.



Two things were the phenomena that catapulted the fame of the drug. On the one hand, unlike other older drugs, the disclosure of the drug, from advertising and specialists, placed a strong emphasis on the scientific component of its operation. Talking about the efficacy of benzodiazepines meant beginning to talk about what they produced in the brain as they interacted with neurotransmitters. This opened up a completely new field for modern medicine, since if the anxiolytics worked, they were because they repaired a biochemical imbalance, that is, a physical problem. Never again fancy or hysteria: anxiety was a disorder that had to be treated with medication.



On the other hand, according to Katherine Sharpe in his book The Age of Zoloft: How the antidepressants made us happy, let us fall and changed who we are, was the subject of the discredit of Freudian psychotherapy. In the 60's began the mass boredom of people who during the last two decades had tried to cure their emotional problems with this type of treatment. Frustrated patients began to complain that psychoanalytic therapy was expensive and time-consuming, sometimes without even producing effective results. Why not use drugs better? Although they did not deliver a definitive solution, a few hours of calm a day were sufficient for the burdened patients.



Until the early 1990s the long reign of diazepam was unstoppable, then it began to be rapidly replaced by Alprazolam, a different type of benzodiazepine, whose metabolization time was much shorter and eliminated the sensation of sedation so characteristic of the previous drug. It would also start the extreme popularity of Prozac, which continues to promise to treat anxiety in the long run. Neither of them would have achieved so much fame had it not been for the road paved by the diazepam.



At the end of the year, the era of this popular drug is finally over. Although its sales are still interesting (48.7 million prescriptions over the past year), Roche has decided to close the mythical Nutley plant to open, in 2013, a smaller research office in New York, in order to Explore the drugs of the future. Who knows if any of their findings will change the pharmaceutical industry and our lives again.